Cortisol and Imaginal Exposure in Posttraumatic Stress Disorder: a Case Report
نویسندگان
چکیده
Imaginal exposure is closely associated with hippocampal processing of traumatic memory. The hippocampus is a target for glucocorticoids which influence memory retrieval and stress response. Glucocorticoid secretion in response to imaginal exposure has not been investigated. We measured subjective distress and salivary cortisol during the 1 and the 20 exposure session in a patient with PTSD. Despite considerable arousal and anxiety, cortisol did not increase during the first exposure. During the 20 exposure there was a marked reduction of distress, although cortisol values did not differ from exposure 1. The response of glucocorticoids to imaginal exposure and mechanisms of the lacking cortisol response need further research (German J Psychiatry 2002;5:75-77).
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